The principal cytochrome P450 isoenzyme concerned appears being CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. Somewhere around 85% of an oral dose seems while in the urine inside of 24 several hours of administration, most given that the glucuronide conjugate, with modest amounts of other conjugates and unchanged drug (see OVERDOSAGE) for toxic